Summer Intern - DMPK DMPK South San Francisco, California ------------ Description SUMMARY: At MyoKardia, were ing precision medicine where we feel it is needed most: altering the course of cardiovascular disease. Become part of it all as a MyoKardia Summer Intern. Weve launched an exciting internship program for students who are looking to gain valuable work experience in a collaborative, values-based company on the cutting edge of precision medicine. MyoKardias summer internship program will take place over a 10 to 12-week period, with both science-based and general corporate roles. Summer interns have the opportunity to work on interesting projects with direct mentoring from an intern manager. We are driven by two great passions: improving the lives of our patients and engaging in innovative science to make it possible. Come help us make a difference as a MyoKardia Summer Intern. MyoKardia has a summer internship available in the Drug Metabolism and Pharmacokinetics department. ESSENTIAL DUTIES AND RESPONSIBILITIES: The intern will perform lab work toward the completion of a project under the guidance of DMPK staff members. The project would include the summer intern learning and implementing basic pharmacokinetic principles regarding the free drug hypothesis, in vitro techniques to examine unbound drug concentration in plasma and tissues, and how to use high performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) methods for determining free drug concentrations. With close guidance and mentoring, the intern would compile and absorb the appropriate up-to-date literature on plasma protein and tissue drug binding methods and the successful incorporation of corresponding techniques at MyoKardia. During the final week of the internship, the intern will present their findings in an oral presentation at a meeting attended by MyoKardia scientists and staff. EDUCATION/EXPERIENCE/SKILLS: In order to be eligible for the MyoKardia Summer Internship Program, the student must be a currently-enrolled undergraduate or graduate student, and have finished at least 4 semesters or 6 quarters of undergraduate study before the beginning of the Summer Program. Applicants with an academic background (GPA of at least 3.0) and strong interest in biology, biochemistry, chemistry, or analytical chemistry are preferred.