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Research Associate 1 - Biophysical

Charles River Laboratories

Charles River Laboratories

Research Associate 1 - Biophysical

Shrewsbury, MA
Full Time
Paid
  • Responsibilities

    ESSENTIAL DUTIES AND RESPONSIBILITIES:

    • Independently perform laboratory activities including but not limited to reagent preparation, laboratory maintenance/monitoring of equipment, routine testing of client samples, and generation of routine cGMP and R&D reports.
    • Perform a variety of BioPhysical laboratory experiments, tests and procedures following well-defined techniques and guidelines, including:
    • Analytical Ultracentrifugation (AUC) - NOT INVOLVED
    • Size Exclusion HPLC-MALLS (SEC-MALLS)- HPLC
    • Differential Scanning Calorimetry (DSC)
    • Intrinsic Tryptophan Fluorescence (ITF)
    • Fourier Transform Infrared (FTIR)
    • Dynamic Light Scattering (DLS)
    • Protein Binding via SPR-Biacore
    • Circular Dichroism (CD) - IDEAL
    • Analyze data and report results of experiments and procedures. - anyone that's fully trained on an assay - from start to finish, have a project, do the analysis,
    • RA- complex projects with Scientist, the RA would do the in lab performance, and data analysis - mix of both independent - partnership
  • Qualifications

    MINIMUM QUALIFICATIONS:

    • Bachelor’s Degree (B.S.), or equivalent, in biochemistry, chemistry or related discipline.
    • Biology, biochemistry, chemistry, analytical background - some biotech background
    • 3-5 years related industry experience in a biophysical science area in the Pharmaceutical, Biotech or contract (CRO) laboratory environment.
    • An equivalent combination of education and experience may be accepted as a satisfactory substitute for the specific education and experience listed above
    • Knowledge of cGMPs or regulatory affairs pertaining to the pharmaceutical and biological industries is preferred.
    • Knowledge of basic protein /peptide biophysical techniques and ability to operate typical laboratory equipment, specifically HPLC, spectrophotometer, dialysis/buffer exchange via SPE, and other laboratory equipment a plus.
    • Strong organizational and prioritization skills required.
    • Attention to detail and accuracy a must.
    • Must possess excellent interpersonal skills to maintain communication across functional groups.
    • Must have strong written and verbal communication.
    • Basic Microsoft Office skills are required.
    • Ability to understand and use internal software programs such as LIMS required.
  • Benefits

    Outstanding benefits, health, eye, dental. We are:

    • The leading global pharmaceutical, biotechnology, agrochemical, government, and academic organization
    • Key supporters in the development of >92% of the drugs approved by the FDA
    • Rated #1 among our region's top 100 companies in the 14th annual "Globe 100" rankings
    • Named "Company of the Year" by Boston Globe
    • Recognized in Bloomberg’s Gender-Equality Index
    • A proud employer of 19,000 impressive individuals nationwide
    • 70 years young
  • Industry
    Biotechnology
  • About Us

    Charles River Laboratories is a visionary leader in the development and delivery of advanced drug therapies. We provide essential products and services to pharmaceutical and biotechnology companies, government agencies and leading academic institutions around the globe, to help accelerate their research and drug development efforts. At Charles River, we view every day as an opportunity to improve global health and people's lives. Our dedicated employees are focused on providing clients with exactly what they need to improve and expedite the discovery, early-stage development and safe manufacture of new therapies for the patients who need them.