At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Pharmacokinetics & Pharmacometrics

Job Category:

Scientific/Technology

All Job Posting Locations:

Raritan, New Jersey, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine.

Johnson and Johnson Innovative Medicine, a division of Johnson & Johnson's Family of Companies is recruiting for a Clinical Pharmacology and Pharmacometrics Post Doctoral Fellow to be located in Raritan, NJ; Titusville, NJ or Spring House, PA.

The Clinical Pharmacology and Pharmacometrics (CPP) department within Johnson & Johnson Internal Medicine develops and applies quantitative methodologies (population PK and PKPD analysis, disease progression, etc. across all phases of drug development and across different modalities.

CPP is sponsoring a post-doctoral fellow to train early career professionals who can contribute to our goal of developing innovative medicines. The post-doctoral fellow will work on one or multiple projects to develop and apply novel methodology designed to increase the speed and accuracy of decision making in drug development. Working with scientific mentors, the fellow will expand in-house knowledge and capabilities in pharmacometrics, exposure-response, and related methodology (e.g., deep learning, causal inference).

The post-doctoral fellow is expected to have recently finished their PhD training in a related discipline and seek formal training for a career in clinical pharmacology/pharmacometrics. The post-doctoral fellow will work under one or more scientists who will provide mentorship during the 2-year program. While the postdoctoral fellow will contribute scientifically and technically to projects, the program will also help develop their leadership skills and ensure both internal and external visibility to the scientific community via external presentations and publications.

The Post-Doctoral Fellow will be involved in various activities to support Research and Development in areas ranging from preclinical to early/late stage clinical development which may include the following activities:

• Advance the development of fit-for-purpose mathematical models to inform clinical study design, dose selection, and/or sub-population discovery through identifying and addressing critical knowledge gaps using modeling and simulation approaches. The specific project(s) will be tailored to the expertise of the candidate and may include assessment of antibody drug antibody (ADA) effects on population pharmacokinetics, deriving learnings from quantitative systems pharmacology models to inform empirical or mechanism-based PK-PD and exposure-response models, or investigation of novel methodology to screen covariates for safety/efficacy relationships.)
• Develop flexible tools for data visualization, pharmacometrics analysis and report automation and standardization
• Identify and improve processes and workflow, develop innovative thinking, inform strategic decision making, and implement new methodologies when applicable

Minimum Qualifications / Experience

• PhD in Pharmacology, Pharmacokinetics, Pharmaceutical Sciences, Biostatistics, Engineering, Bioinformatics, Computer Science, Applied Mathematics, Systems Biology, or Computational Biology

Minimum Technical Knowledge and Skilla

• Fluent in written and spoken English
• Demonstrated computational skills related to pharmaceutical or biomedical research, and strong hands-on programming skills in R, MATLAB, python or Julia is required; experiences with additional PKPD modeling tools (e.g., NONMEM) is are desired
• Excellent interpersonal skills with an ability to build positive relationships with colleagues from a diverse set of backgrounds and work with senior members and cross-functional teams
• Detail-oriented, highly organized, and able to manage multiple tasks
• Ability to function in a fast-paced environment and a creative problem solver

Minimum Non-Technical Competencies and Skills

• Good written and oral communication skills (communication)
• Ability to build and enhance working relationships inside and outside the department; ability and willingness to work in a cross-functional team environment (building strategic working relationships)
• Ability to multi-task and prioritize assignments, establishing courses of action for self and others to ensure that work is completed efficiently in a timely manner (planning and organizing)
• Adding value to the organization assuming responsibility and accountability for successfully completing assignments or tasks (delivery of results)
• Actively identifying new areas for learning and application to the job (continuous learning)
• Good sense of cultural sensitivity and diversity (cultural diversity)
• Good project management skills (program management)
• Self-motivated with the ability to work independently with minimal supervision (personal accountability)

Other Requirements

• Estimated travel of about [5%] of time

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

The anticipated base pay range for this position is:

$74,000-$124,200

Additional Description for Pay Transparency:

Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation –120 hours per calendar year Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year Holiday pay, including Floating Holidays –13 days per calendar year Work, Personal and Family Time - up to 40 hours per calendar year Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member Caregiver Leave – 10 days Volunteer Leave – 4 days Military Spouse Time-Off – 80 hours Additional information can be found through the link below. https://www.careers.jnj.com/employee-benefits

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