At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Translational Discovery & Development Biomarkers

Job Category:

People Leader

All Job Posting Locations:

Cambridge, Massachusetts, United States of America, San Diego, California, United States of America, Spring House, Pennsylvania, United States of America, Titusville, New Jersey, United States of America

Job Description:

Johnson and Johnson is recruiting for a Director, Neuropsychiatry Clinical Translational Lead to be located in La Jolla, CA, Titusville, NJ, Spring House, PA, or Cambridge, MA.

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Neuroscience team tackles the world’s toughest brain health challenges including multiple sclerosis, Alzheimer’s disease, Parkinson’s disease, myasthenia gravis, epilepsy, major depressive disorder, bipolar disorder, schizophrenia, and autism. This patient-focused team helps address some of the most complex diseases of our time.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

The Neuroscience Precision Measures Team is an integrated group of scientists that supports the mission to deliver precision therapeutics to patients with CNS disorder in the areas of neuropsychiatry, neurodegeneration and ophthalmology. The team is composed of disease experts, biomarker scientists, computational biologists, and experts in imaging and digital health, partnering closely with the Neuroscience Discovery and Development organizations to enable advancement of our industry leading pipeline of novel mechanisms.

The Precision Measures team advances measurement based on human data from fluids, tissues, high-dimensional biology, and neuroimaging to support the end-to-end portfolio. Together with our partners, the PM group will provide the key learnings/insights on the next wave of novel therapies. Precision Measures has a broad remit stretching from support of discovery with human data to support target selection, through development of novel decision-making biomarkers for early phase clinical trials, biomarker support of regulatory filings, post-market publications and diagnostics.

The Director, Neuropsychiatry Clinical Translational Lead position is a senior leadership role within the Neuroscience Precision Measures team, supporting programs clinical stage programs in Neuropsychiatry. This position reports to the Head of Quantitative Imaging and Clinical Biomarkers, and will lead and coordinate cross-functional Measurement Development teams for clinical phase neuropsychiatry programs. The Director will coordinate the translational measurement strategy including patient stratification approaches, advanced endpoints, creating and implementing innovative biomarker strategies by partnering and aligning experts across the Precision Measures, Neuroscience and broader J&J Innovative medicines organization. This role serves as a key member of Compound Development Teams convening the translational subteams, and will lead preparation for Measurement Development Forums to align with and receive input from key members of the Neuroscience Leadership Team. The Director will manage the cross-functional team to turn ideas into plans, evaluating feasibility and risk, performance requirements, timelines, deliverables and communication.

Integration of insights from the external ecosystem, including literature, conferences, partnership and consortia, aligned to program goals and timelines. The successful candidate will have a strong track record, expertise and collaborative base in the field of neuropsychiatry.

The Director, Precision Measures, will be accountable for ensuring the group’s strategic direction, proactive preparedness for governance decisions, the timely creation and implementation of high caliber translational biomarker plans in support of key milestones for clinical phase programs. The successful candidate will be responsible for overseeing the construction of translational data packages, including strategies for target engagement, expression and predictive response biomarkers to enable patient stratification.

Responsibilities:

• Lead cross-functional teams of scientists to develop and execute clinical biomarker plans for clinical stage compounds, establishing evidence generation plan for novel measurements, analyze and interpret clinical data, driving decision making for clinical assets.

• Lead and shape the design and on-time execution of program translational strategies integrating both disease and pathway approaches to address target engagement and expression, patient segmentation and indication potential.

• Collaborate with Clinical Development, Precision Measures leadership, Data Science & Digital Health to establish strategies for the development and implementation of clinical biomarkers.

• Partner with Compound leads to integrate clinical translational science findings into evolving programs.

• Lead and drive efforts to engage in collaborations with external partners/academic institutions having strong capabilities in translational science and medicine.

• Support Business Development, including due diligence activities.

Qualifications

• PhD, MD or MD/PhD required

• Minimum of 6-12 years of industry or relevant experience where direct ‘hands-on’ experience in neuroscience biomarker development is required.

• Depth of experience with several different therapeutic platforms preferred (biologics, small molecules and/or gene/RNA).

• Exceptional communication and collaboration skills are required

• Track record of developing and implementing impactful biomarker and translational plans is essential.

• Experience leading matrix teams is required.

• Training in translational sciences or basic neuroscience is strongly preferred.

• Subspecialty training in neuropsychiatry is preferred

• Dynamic entrepreneurial mindset

The anticipated base pay range for this position is $160,000 to $276,000.

Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance.

Subject to the terms of their respective plans, employees are eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company’s long-term incentive program.

Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits:

• Vacation –120 hours per calendar year

• Sick time - 40 hours per calendar year; for employees who reside in the State of Washington –56 hours per calendar year

• Holiday pay, including Floating Holidays –13 days per calendar year

• Work, Personal and Family Time - up to 40 hours per calendar year

• Parental Leave – 480 hours within one year of the birth/adoption/foster care of a child

• Condolence Leave – 30 days for an immediate family member: 5 days for an extended family member

• Caregiver Leave – 10 days

• Volunteer Leave – 4 days

• Military Spouse Time-Off – 80 hours

Additional information can be found through the link below.

https://www.careers.jnj.com/employee-benefits

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource.

#LI-Hybrid

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.