At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Biotherapeutics R&D

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for an Experienced Scientist, Viral Vector Downstream Process to be located in Spring House, PA.

Purpose:

The Experienced Scientist, Viral Vector Downstream Process position in the Cell Therapy Platform & Discovery group of Therapeutics Discovery offers an exciting opportunity to help develop novel Cell & Gene Therapies for unmet medical needs. We are investigating the use of engineered viral vectors for ex vivo and in vivo gene delivery to T cells to treat cancer. We are seeking a highly motivated downstream process scientist to develop and implement vector purification strategies to enable preclinical studies. Do you have industry experience with downstream viral vector process development and the ability to thrive in a cross-functional team? Come join us in our mission to build the next generation of Cell & Gene Therapies for Oncology.

You will be responsible for:

• Design, optimize, and execute downstream purification processes to improve yield, purity, and stability of lentiviral vectors (LVV)
• Independently operate and maintain chromatography and filtration systems (e.g., TFF, depth filtration) for virus purification
• Collaborate with stakeholders to ensure timely delivery of purified, quality-controlled vector lots to support preclinical studies
• Maintain detailed records for vector productions and process development experiments to ensure traceability and data integrity
• Contribute to a collaborative, creative, and rigorous culture of scientific discovery

Qualifications:

• BS or MS in Biological Engineering, Chemical Engineering, Virology, Biology, or related field with 2+ years of related experience is required. Industry experience is preferred.
• Experience with viral vector downstream processing methods, including column chromatography (Akta), is required
• Expertise in LVV purification is preferred
• Familiarity with analytical techniques for lentiviral vectors is preferred
• Strong critical, scientific, and strategic thinking skills are required
• Strong organizational skills, with the ability to independently manage multiple projects in parallel, are required
• Demonstrated ability to work collaboratively in cross-functional teams is required
• This role may require up to 5-10% travel.

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

#LI-Onsite

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.