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Developing innovative therapeutics to treat diseases like Alzheimer’s disease, various types of cancers and infectious diseases like Hepatitis B, influenza is our passion. In this endeavor, we are seeking to recruit new talent for the comprehensive analyses of high-dimensional datasets using state-of-the-art data science methods applied to drug discovery programs. The position is opened at Spring House (PA), a headquarters of Janssen Research & Development. We significantly increased our investment into the workforce for data analysis pipelines with the emphasis in current cutting-edge technologies to support future Artificial Intelligence-driven drug design and discovery.
Janssen Research & Development L.L.C., is looking for the 2-year postdoctoral fellow to support drug design and discovery projects using machine learning approaches with emphasis on transfer learning and deep learning. Deep learning techniques have already shown promise for small molecule projects in Janssen, yet most of those models require a significant amount of data, while many of the ADMETox-related pipelines generate significantly smaller datasets that require transfer learning to integrate them successfully into the predictive pipelines.
This position will support small molecule design and optimization using machine learning techniques by integrating millions of data points coming from heterogeneous data sources: chemical structure, microscopy images, and various omics experiments. The primary goal is the improvement of the predictive pipelines to increase safety and efficacy of the drug candidates and decrease the time needed to progress hit compound to lead compound to compound in clinical trials.
Main responsibilities would include the development of predictive models and their testing in real projects that would require interaction with chemists, biologists, and data scientist and further model optimization if needed. We are looking for candidates with a track record in deep learning and preferably experience working with chemical or biological data.
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.