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With $76.5 billion in 2017 sales, Johnson & Johnson is the world's most comprehensive and broadly-based manufacturer of health care products, as well as a provider of related services, for the consumer, pharmaceutical, and medical devices markets. There are more than 250 Johnson & Johnson operating companies employing over 125,000 people and with products touching the lives of over a billion people every day, throughout the world. If you have the talent and desire to touch the world, Johnson & Johnson has the career opportunities to help make it happen.

POSTDOCTORAL FELLOW, CAR-T DRUG PRODUCT PROCESS DEVELOPMENT

The CAR-T Drug Product Development team in Janssen BioTherapeutics Development (BTD) is seeking an energetic, highly motivated Postdoctoral Fellow to develop next generation CAR-T drug product and manufacturing process platforms. This post-doctoral position will provide a rare opportunity to execute pioneering bench-to-bedside research with the intent of developing innovative approaches to deliver novel CAR-T based therapeutics to patients. Upon completion of the postdoctoral program, the Fellow will have acquired valuable career experience that enables entry into translational academic settings, biotech-related opportunities, and/or continued development in large pharma.

At Janssen, Postdoctoral fellows are trained by expert scientists working at the cutting edge of drug discovery and development.  The BTD organization partners with the Discovery and Clinical divisions and supports a wide range of Therapeutic Areas including Oncology, Neuroscience, Cardiovascular and Metabolism, Immunology, and Infectious Diseases.  BTD is committed to foster a working environment that encourages the company's commitment to equal employment opportunity and the value of a diverse work force. The successful candidate will learn from and contribute to an industry-leading drug discovery program that has brought numerous quality therapeutics to patients and has made significant contributions to human health. She/He will collaborate and participate in cross-functional team discussions, gaining insight into many aspects of biotherapeutic discovery and development. 

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

The Postdoctoral Fellow is expected to:

• Evaluate and identify opportunities/new technologies to improve CAR-T Drug Product manufacturing process
• Independently design and establish a strategic innovation strategy to develop next generation CAR-T drug product and manufacturing process platforms
• Collaborate with internal and external partners to develop next generation CAR-T drug product development strategies, including design of experiments, execution of the planned experiments, and optimization of the process steps
• Deliver reports, summaries, and presentations supporting experimental results
• Present research findings and data to the group; interact and collaborate with cross-functional teams and external partners, and present findings
• Ensure data integrity and maintain compliance with general laboratory operations, all appropriate SOPs for laboratory work, data recording, and laboratory equipment
• Maintenance of detailed records, notebooks in a GMP compliant manner, safety, and environmental requirements is expected

• Ph.D. in Chemical Engineering, Bioengineering, Biomaterials, Biological Sciences, or a related field is required.
• Experience in cell culture and handling is required.
• Experience in cell-based assays and flow cytometry analysis is preferred.
• Working knowledge in T-cell biology and immunology is preferred.
• Working experience in CAR-T biology and process is preferred
• Previous experience and a good track record in development of new technologies/processes is required. 
• Ability to challenge status quo, and develop intellectual insights is required.
• Ability to drive independently the innovation projects including design and execution of the strategy/studies is required.
• Candidates must be detail-oriented, highly organized and able to manage multiple tasks, handle tight timelines and deliver quality data
• Experience maintaining written records of work in the form of laboratory notebooks (paper or electronic) is required
• Excellent communication and interpersonal skills, capable of delivering data-based reports in all relevant formats, is required

PRIMARY LOCATION United States-Pennsylvania-Malvern- ORGANIZATION Janssen Research & Development, LLC. (6084) JOB FUNCTION Administration REQUISITION ID 2234190109

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