Johnson & Johnson is seeking a POSTDOCTORAL FELLOW – PHARMACOKINETICS AND PHARMACODYNAMICS (CELLULAR THERAPIES) to join our team in the DMPK, Preclinical Sciences and Translational Safety (PSTS. This position is located in Spring House, PA, but does have the option to be remote!

At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal. Janssen Research & Development, LLC is part of the Janssen Pharmaceutical Companies.

The Janssen R&D Discovery, Product Development, & Supply (DPDS) Postdoctoral Fellowship Program helps early career scientists gain the training and experience needed to further their careers, while addressing the needs of global healthcare. Janssen DPDS Postdocs work side-by-side with Janssen scientists on innovative research projects and have the opportunity to present and publish their work. They also learn the functional role of scientists in the pharmaceutical industry and receive valuable career advice from mentors while building a network of professional contacts and developing the skills needed to advance their careers.

This is a post-doctoral position within the DMPK function, Preclinical Sciences and Translational Safety (PSTS). The post-doctoral fellow, under supervision, will be responsible to research and deliver on critical questions in the area of translational PK/PD and first in human dosing approaches for cell therapies (CAR-Ts) through data collection and meta-analysis. The candidate will be provided opportunities to train and apply hands-on PK/PD M&S techniques towards projects goals.

The position is expected to closely interact with cell therapy project team members/ leaders from cross-functions within PSTS, therapeutic discovery, and oncology therapeutic area to complete assigned tasks and achieve project goals. Additional expectations include, attending in-house/external seminars and scientific meetings as appropriate to develop professional competency and support team goals; present findings at team meetings, in-house research forums, and national/international conferences, where applicable; strive to publish results in peer-reviewed journals.

THE CANDIDATE’S RESPONSIBILITIES WILL INCLUDE:

• Systematic literature review and data compilation

• Meta-analysis and PK/PD modeling

• Preclinical to clinical translation for doses of cell therapies

• Development, training, conferences, internal meetings & symposia

QUALIFICATIONS

REQUIRED MINIMUM EDUCATION

• PhD Required Years of Related Experience: 0-1

REQUIRED KNOWLEDGE, SKILLS, AND ABILITIES:

• Ph.D. degree in Pharmaceutical Sciences, Clinical Pharmacology, Biological Sciences, Biological or Chemical Engineering or equivalent with a track record of sound scientific achievement through publications is required.

• Background and understanding of pharmacokinetics/pharmacodynamics (PK/PD) concepts and/or understanding of cell therapies is preferred

• Proficiency in quantitative (correlative and statistical) approaches to perform meta-analysis and/or hands-on experience performing mechanism-based modeling and use of quantitative approaches in describing PK/PD systems using preclinical and clinical pharmacology data for biologics is desired. Proficiency in the use of modeling software such as WinNonlin/Phoenix, Monolix, or similar ones is desired

PREFERRED AREA OF STUDY:

• Pharmaceutical Sciences, Clinical Pharmacology, Biological Sciences, Biological or Chemical Engineering or equivalent

PREFERRED KNOWLEDGE, SKILLS AND ABILITIES:

• Background and understanding of pharmacokinetics/pharmacodynamics (PK/PD) concepts and/or understanding of cell therapies

• Proficiency in quantitative (correlative and statistical)  approaches  to  perform  meta-analysis  and/or hands-on  experience performing mechanism-based modeling and use of quantitative approaches in describing PK/PD systems using preclinical and   clinical   pharmacology data for biologics  

• Proficiency in the use of modeling software such as WinNonlin/Phoenix, Monolix, or similar ones

Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

For more information on how we support the whole health of our employees throughout their wellness, career and life journey, please visit www.careers.jnj.com.

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.