At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Career Programs

Job Sub Function:

Post Doc – Drug Discovery & Pre-Clinical/Clinical Development

Job Category:

Career Program

All Job Posting Locations:

Cambridge, Massachusetts, United States of America

Job Description:

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Ophthalmology team tackles the world’s toughest ocular health challenges, particularly in age-related macular degeneration (AMD), with a focus on geographic atrophy (GA). This patient-focused team helps address some of the most complex diseases of our time.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine.

Johnson & Johnson Innovative Medicine R&D is recruiting for a Postdoctoral Researcher studying Retinal Pigment Epithelium (RPE) biology in the blinding disease of age-related macular degeneration (AMD) and Geographic Atrophy (GA). This is a fixed-term position for 2 years, located in Cambridge, MA, with potential for extension to 3 years. This exceptional scientist will join the Ophthalmology Discovery team within the Neuroscience Discovery organization. In this role, the individual will bring expertise in understanding the role of RPE integrity and metabolic health in the progression of AMD/GA disease. The scientist will collaborate closely with a cross-functional team, utilizing in vitro iPSC models and in vivo models, and samples from human donors to understand the disease biology and describe the implication of specific pathway disturbances to identify disease modifiers and support ophthalmology discovery strategies. These efforts will help ensure that regulators, payers, physicians, and patients clearly understand the rationale behind treatment decisions while providing new insights into the retinal mechanisms underlying ocular diseases.

You will be part of a dynamic, interdisciplinary ophthalmology and neuroscience team with diverse expertise and focus areas.

Key Responsibilities:

Work within an ophthalmology team focused on understanding RPE biology in AMD/GA, particularly relating to pathways implicated in cellular metabolism.

Leverage expertise in imaging techniques and molecular and cellular approaches to evaluate and profile RPE metabolism and functions, combined with validation in existing animal models and human donor samples.

Identify gaps, key scientific questions, and project needs; utilize expertise and facilitate collaborations to address these questions.

Establish, develop, and optimize in vitro models using RPE cells and live cell imaging techniques for a better understanding of biology.

Collaborate with cross-functional teams to enhance teamwork in the industry, leverage resources, and integrate information from different perspectives for comprehensive analysis.

Present findings to internal and external stakeholders, building a network for better communication.

Qualifications

Required:

PhD in ophthalmology, biology, biochemistry, biotechnology, cellular and molecular biology, immunology, neuroscience, or a related field.

Demonstrated expertise and a track record of scientific contributions in biological research.

Strong problem-solving skills, and proficiency in experimental design, data analysis, and interpretation.

Understanding of drug discovery principles and their application in research programs.

Ability to clearly communicate technical work to a diverse audience.

Preferred:

Prior experience in ophthalmology.

Prior experience in healthcare, biopharma, or life sciences.

Experience in driving cross-functional scientific collaborations and external partnerships.

Adherence to established procedures for recording, documenting, and retaining scientific information.

Familiarity with regulatory compliance and quality standards in scientific research.

Contributions to open-source projects, publications in peer-reviewed journals, or presentations at relevant conferences.

The anticipated base pay range for this position is :

$77,000-$124,200

Additional Description for Pay Transparency:

The Company maintains highly competitive, performance-based compensation programs. Under current guidelines, this position is eligible for an annual performance bonus in accordance with the terms of the applicable plan. The annual performance bonus is a cash bonus intended to provide an incentive to achieve annual targeted results by rewarding for individual and the corporation’s performance over a calendar/performance year. Bonuses are awarded at the Company’s discretion on an individual basis. Employees and/or eligible dependents may be eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability, business accident insurance, and group legal insurance. Employees may be eligible to participate in the Company’s consolidated retirement plan (pension) and savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Employees are eligible for the following time off benefits: Vacation – up to 120 hours per calendar year Sick time - up to 40 hours per calendar year; for employees who reside in the State of Washington – up to 56 hours per calendar year Holiday pay, including Floating Holidays – up to 13 days per calendar year of Work, Personal and Family Time - up to 40 hours per calendar year Additional information can be found through the link below. http://www.careers.jnj.com/employee-benefits The compensation and benefits information set forth in this posting applies to candidates hired in the United States. Candidates hired outside the United States will be eligible for compensation and benefits in accordance with their local market.

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.