At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Career Programs

Job Sub Function:

Post Doc – Drug Discovery & Pre-Clinical/Clinical Development

Job Category:

Career Program

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Postdoctoral Scholar, Peptide Chemistry to join the Global Discovery Chemistry team within the Therapeutics Discovery Organization in Springhouse, PA.

Purpose:

The focus of this position is to design and synthesize peptides to understand and improve permeability via passive and active transport. The successful candidate with be a highly motivated and technically skilled individual with a strong background in peptide chemistry. This postdoctoral position will last 24 months and offers an exciting opportunity to drive innovation in this emerging therapeutic modality.

You will be responsible for:

• Apply various chemical peptide modifications to understand factors influencing permeability of peptides to enhance oral bioavailability.
• Design and synthesis of peptides for active targeting approaches including conjugation to ligands
• Work directly with colleagues across GDC, TDS, and TPPIT to evaluate results and design optimized peptides
• Development, training, conferences, internal meetings & symposia

Required Knowledge, Skills and Abilities:

• A Ph.D. in peptide, synthetic organic, or medicinal chemistry. Degree must be completed within the past 3 years or to be completed within the upcoming 6 months.
• Strong background in peptide chemistry and characterization techniques
• Strong track record of achievement in the synthesis of complex molecules and/or synthetic methodology development, with deep knowledge of modern synthetic & analytical techniques
• Proven track record of scientific contributions including peer reviewed publications, patents and presentations
• Strong interpersonal skills and experience in collaborative, multidisciplinary team environments.
• Excellent oral and written communication skills

Preferred Knowledge, Skills and Abilities

• Experience with parallel peptide synthesis platforms
• Permeable and/or orally bioavailable peptides a plus
• Oral peptide design strategies including incorporation of unnatural amino acids
• Strong track record of scientific contributions including peer reviewed first-author

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.

Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.