At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at https://www.jnj.com

Job Function:

Discovery & Pre-Clinical/Clinical Development

Job Sub Function:

Pharmacokinetics & Pharmacometrics

Job Category:

Scientific/Technology

All Job Posting Locations:

Spring House, Pennsylvania, United States of America

Job Description:

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist, Translational PK/PD to be located in Spring House, PA.

A pre-identified candidate for consideration has been identified. However, all applications will be considered.

Purpose: We are looking for a Translational PK/PD scientist to join our Translational Pharmacokinetics, Pharmacodynamics and Investigational Toxicology (TPPIT) group, part of Preclinical Sciences and Translational Safety (PSTS) organization. This position will be responsible for serving as a translational PK/PD representative on project team , contribute towards driving Non-Clinical PK, ADME and PK/PD strategy and execution to enable timely recommendations for discovery programs, drive preclinical development through IND/CTA filing. Using both experimental and computational tools, this individual will contribute towards relevant forward and reverse translation for projects and platform efforts.

You will be responsible for:

• Represent function and provide translational PK/PD support on project teams starting from early discovery through IND/CTA
• Demonstrates fundamental knowledge of PK/ADME concepts and conducts PK/PD data analysis to inform FIH dose selection and efficacious dose projections, design relevant experiment and modeling strategy, and integrate PK/ADME/PD data with pharmacology and toxicology profiles to effectively inform program strategy and decisions.
• Collaborate closely with biologists, chemists, protein engineers, toxicologists, bioanalytical scientists, clinical pharmacologists and clinicians to advance portfolio programs
• With oversight, author relevant sections of internal and regulatory submission documents and reports.

Qualifications:

Education:

• Minimum of a Bachelor’s Degree is required.

Skills/Experience:

• Minimum of 6 years of relevant pharmaceutical experience is required.
• Strong understanding of PK, ADME and PK/PD with ability to translate data into project relevance, as part of anticipating and mitigating program challenges is required.
• Excellent interpersonal, organizational, oral/written communication and teamwork skills are
• Hans-on experience in at least one of the modeling and simulation software is preferred
• Prior experience in novel biologics modalities is preferred.
• Good publications record is required

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson & Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please contact us via https://www.jnj.com/contact-us/careers or contact AskGS to be directed to your accommodation resource.

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Push the boundaries of science to transform health—and your career.

Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

Accelerate your career while changing the world.

Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.