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Post-Doctoral Fellow, CAR-T Cell Therapy Formulation

Learn more about Johnson & Johnson
Johnson & Johnson

Johnson & Johnson

Post-Doctoral Fellow, CAR-T Cell Therapy Formulation

Spring House, PA
Full Time
Paid
  • Responsibilities

    At Johnson & Johnson, we use technology and the power of teamwork to discover new ways to prevent and overcome the world’s the most significant healthcare challenges. Our Corporate, Consumer Health, Medical Devices, and Pharmaceutical teams leverage data, real-world insights, and creative minds to make life-changing healthcare products and medicines. We're disrupting outdated healthcare ecosystems and infusing them with transformative ideas to help people thrive throughout every stage of their lives. With a reach of more than a billion people every day, there’s no limit to the impact you can make here. Are you ready to reimagine healthcare?

     

    Here, your career breakthroughs will change the future of health, in all the best ways. And you’ll change, too. You’ll be inspired, and you’ll inspire people across the world to change how they care for themselves and those they love. Amplify your impact. Join us!

     

    Janssen BioTherapeutics is searching for an energetic, highly motivated POSTDOCTORAL FELLOW to carry-out development of novel formulation and delivery processes for autologous and allogeneic CAR-T/NK cell adoptive cell therapy for oncology.  Present CAR-T cell immunotherapies show impressive clinical responses, with two CAR-T cell products approved by the FDA for the treatment of B cell malignancies. This role will be located in Spring House, PA.

    Through exploring and leveraging new insights this postdoctoral fellow will:

    • Conduct research and development activities to design optimal formulation and delivery processes of CAR-T/NK cell therapy products as well as lenti- and adeno-viruses that are yet unexplored and define the parameters for building the best-in-class adoptive cell therapy drug products.
    • Design and implement analytical methods with sufficient sensitivity to characterize adoptive cell therapy products as well as lenti/adenoviral products
    • Be rewarded with an excellent opportunity to interact with various teams focused on cutting-edge engineered cell therapy platform development.
    • In addition, upon completion of the postdoctoral program, the Fellow will have acquired valuable career experience that enables entry into process and product development field, biotech-related opportunities, and/or continued development in large pharma.
  • Qualifications
    • Recent Ph.D. in Immunology with a strong background in T cell and/or other immune cells biology
    • A working background in T cell biology with hands on experience in cell biology, and assay development is a must.
    • A working experience with bioinformatics computational tools to analyze Flow cytometry or genomic datasets will be a plus
    • A working experience in lenti- or adeno-viruse generation is highly desired
    • Candidate must be able to work permanently in the US.
    • Candidates must display an ability to independently design and execute research.  
    • In addition to a broad knowledge of immunology and oncology, we are seeking an individual with deep intellectual curiosity, and excellent communication and interpersonal skills.

     

    Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

  • Industry
    Hospital and Health Care
  • Fun Fact
    We aspire to be the world's healthiest work force, offering group fitness classes, beach volleyball courts, bicycle desks, and more!
  • About Us

    Push the boundaries of science to transform health—and your career.

    Join us and advance life-changing treatments for people who need them most. At Johnson & Johnson, our focus is on improving global health equity and developing MedTech and pharmaceutical innovations that impact the future of health. Using AI and robotics to transform surgery or helping data scientists and clinicians formulate new ways to diagnose and treat disease, this work may sound like sci-fi, but it’s all science, all real, and could be your career. Whatever your background, skills, or career goals, there’s a place for you to help solve some of the world’s most pressing health challenges with us.

    Accelerate your career while changing the world.

    Each of our broadly-based family of companies offers an inclusive and empowering culture and employee benefits (like paid time off to volunteer, transgender-inclusive and same-sex partner health insurance coverage, and more) designed to help you live your best life, however you define it. And our best-in-class learning and development approaches, mentorship, and access to innovators across the world will help you grow your skills and reach your career goals. Because when you're at your best, nothing stands between you and your next breakthrough.