Job Description

ABOUT THIS ROLE  

The Biochemistry and Chemistry Development group (BioCD) is seeking a highly motivated candidate to join the Analytical Development department at Biogen, in Research Triangle Park, NC. The Scientist I will work with their manager and peers in a cross-functional team to advance Biogen’s biologics portfolio on a range of innovative pipeline programs and next generation technology development initiatives. A background in analytical chemistry, protein chemistry or biochemistry especially with separation-based, biophysical and particle sizing methods (chromatography, spectroscopy, electrophoresis, light scattering).

WHAT YOU’LL DO  

• Serve as a technical leader to identify, develop and implement new analytical technologies in various separation, biophysical and particle sizing techniques, such as liquid chromatography (HPLC/UPLC), electrophoresis (CE, icIEF), mass spectrometry (MS), spectroscopy (CD, FTIR), and particle sizing (MALS, HIAC, MFI, AUC) for the characterization of clinical biopharmaceutical products.
• Proactively collaborate and/or represent analytical department in cross-functional teams in planning programs, experimental activities and technology/method implementation/transfers.
• Design, develop and implement assay and operational efficiencies such as with instrument/liquid handling and procedure automation.
• Analyze data, write reports and method protocols, and archive in the appropriate data and document management tools. Contribute to regulatory filings.
• Author technical papers and publish them in peer-reviewed journals. Present at national and international conferences.

 WHO YOU ARE  

You are expected to work independently and with other team members and to plan, conduct, analyze, and document experiments to drive protein therapeutics development and innovation in a highly collaborative and innovative team. We are seeking prior experience in biophysical characterization, analytical method development, protein characterization, and automation of sample handling.

Qualifications

REQUIRED SKILLS 

• B.S. 6+ year of experience in Analytical Chemistry, Protein Chemistry, Biochemistry, or related disciplines
• M.S. 4+years experience in Analytical Chemistry, Protein Chemistry, Biochemistry, or related disciplines.
• Knowledge and expertise in protein structure and analytical/biophysical characterization
• Prior experience in separation and particle sizing techniques: chromatography (size exclusion, anion/cation exchange, hydrophobic/hydrophilic, reversed phase), electrophoresis (CE-SDS and icIEF), and SEC MALS
• Proficiency in good documentation practices, data analysis, reporting and review.
• Strong team player with ability to execute tasks independently and as part of a team.
• Willingness to learn (new methods, drug development processes, new modalities, etc.) and ability to demonstrate scientific curiosity and innovation.
• Good written and verbal communication skills.

PREFERRED SKILLS 

• Ph. D + 0-2 years of experience in Analytical Chemistry, Protein Chemistry, Biochemistry, or related disciplines
• Biophysical characterization
• Experience in analytical method development of chromatography, electrophoresis and mass spectrometry-based techniques
• Experience in automation of sample handling and/or process steps
• Familiarity with different robotic platforms
• Experience with various modes of spectroscopy and multivariate data analysis.
• Familiarity with biophysical and particle characterization techniques such as light scattering

Additional Information

WHY BIOGEN?  

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us as a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.