Job Description

This is for a 6-month full-time co-op from January to June 2021

DNA-Encoded libraries consist of billions of molecules that are screened against targets of interest to generate novel hits to start small molecule drug discovery programs. This screening method generates thousands of potential hits with different enrichment scores. The level of enrichment may not correlate with binding affinity. Also, there is a possibility for high false positive rate as the data is inherently noisy. Selecting true hits can be challenging. Co-op student will work on one or more DEL screening datasets to develop methods to find true hits and derive structure activity relationship information from the data.

Qualifications

To participate in the Biogen Internship Program, students must meet the following eligibility criteria:

•    Legal authorization to work in the U.S.

•    Grade point average of 3.2 or higher preferred

•    At least 18 years of age prior to the scheduled start date

•    Be currently enrolled in an accredited college or university

Additional Qualifications:

The preferred candidate would have demonstrated expertise in several of the following skills: • Experience in data analysis applying statistical and machine learning methods

• Scripting / programming skills

EDUCATION: Ph.D. student pursuing studies in computational chemistry or chemoinformatics

LOCATION: Cambridge, MA

Additional Information

All your information will be kept confidential according to EEO guidelines.