Postdoctoral Research Fellow Immunology and Tumor Stroma/Vasculature Research Date:Jan 3, 2019 Location:Palo Alto, CA, US -Requisition ID:POS000291 Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified itslegacy for over a century. Mercks success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare. Merck is on a quest for cures and is committed to being the worlds premier, most research-intensive biopharmaceutical company. Today, were doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Mercks leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. Be a part of the legacy: MRL Postdoctoral Research Fellow Program The Merck Research Laboratories (MRL) Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide you with an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery. As a postdoctoral fellow in Merck Research Labs, Department of Discovery Oncology, based in Palo Alto CA, you will work in a highly collaborative environment with a team of scientists to design, develop, and validate in vivo/in vitro models to investigate interactions between tumor stroma/vasculature and immune system. The results from this work will improve our understanding of tumor microenvironment in establishing and survival of tumors, particularly in the context of immunology. Responsibilities include but are not limited to: -Disassociating and characterizing cellular components of fresh tumor biopsies from humans and animal models. -Conducting in vitro/cell culture experiments and analyses using standard molecular biology techniques including ELISA, high dimension multi-color flow cytometry, and mRNA profiling. -Conducting in vivo murine tumor model studies to correlate and validate in vitro results. -Data interpretation, manuscript preparation, publication and data presentation. -Contributing to a friendly, safe, and compliant laboratory work environment. mrlpostdoc Qualifications Education Minimum Requirement: -A PhD with less than (3) years of postdoctoral experience OR graduating with a PhD by summer of 2019.Required Experience and Skills: -Isolation and culture of primary immune/stromal cells from freshly isolated human or murine tissues. -Skilled in in vivo murine models in immunology and/or tumor immunology. -Strong interpersonal skills that enable and facilitate collaboration with various groups in Merck Research Labs. -Ability to conceive, design, execute and communicate complex experiments in the field of immunology and/or tumor immunology as evidenced by publications Preferred Experience and Skills: -Knowledge of both human and murine immunology. -Experience in studying endothelial cells and vasculatures. -Experience studying lymphocyte trafficking and homing. -Experience with three dimensional tissue culture models. -Bioinformatics experience, particularly in analyzing RNA-seq results and pathway analyses. Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and were counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, were inventing for life. If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to -. Search Firm Representatives Please Read Carefully: Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity. Please, no phone calls or emails. All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck. No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means. For more information about personal rights under Equal Employment Opportunity, visit: -Merck is an equal opportunity employer, Minority/Female/Disability/Veteran proudly embracing diversity in all of its manifestations. Job:Post-Doctoral Fellow Other Locations: Employee Status:Regular Travel:No Number of Openings:1 Shift (if applicable):N/A Hazardous Materials: Company Trade Name:Merck Nearest Major Market:San Jose Nearest Secondary Market:Palo Alto