ABOUT ABBVIE

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health, and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.

For more information about AbbVie, please visit us at www.abbvie.com.

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COMPUTATIONAL BIOLOGY/BIOINFORMATICS INTERNSHIP OVERVIEW

Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie’s Experiential Interns.

The Computational Biology/Bioinformatics Intern will work with the Computational Genomics team, the Genomics Technology team, and different Discovery CompBio teams (Immunology, Neuroscience) of the Genomics Research Center (GRC) at AbbVie. The GRC is a multidisciplinary center of excellence with expertise in genomic technologies and their application, human genetics, genomic medicine, computational analysis, data integration, genome biology and application of functional genomics.

The Computational Biology/Bioinformatics intern will work with two scientific mentors to systematically compare spatial transcriptomic technologies from Nanostring and 10X Genomics (GeoMX vs. Visium) across different therapeutic area applications. Evaluation will include biological readouts such as mapping of celltypes, phenotyping of tissue microenvironment, differential expression patterns of a celltype based on spatial location and ligand receptor analysis, but also consider practical considerations, such as throughput, eligibility for focused vs. exploratory analysis, resolution, and experimental complexity. At the end of the internship, the intern will be able to analyze different types of spatial transcriptomics data, interpret the results, and provide guidance on the usage of these technologies.

KEY RESPONSIBILITIES INCLUDE:

• Determination of key metrics to comparatively evaluate spatial technologies across different applications

• Implement data analysis workflows and custom scripts for comparative analyses; usage of AbbVie Github

• Data analysis and interpretation; establish and document recommendations for future decisions across therapeutic areas

• Present results in team/group meetings

MINIMUM QUALIFICATIONS

• Currently enrolled in university, pursuing a Master’s or PhD in Computational Biology, Bioinformatics, Biology, Pharmaceutical Science, Computer Science or other related field

• Must be enrolled in university during the internship period

• Knowledge in R or Python programming

• Strong written, verbal and oral communication skills

• Must be organized

PREFERRED QUALIFICATIONS

• Experience in spatial transcriptomics data analysis or in single cell transcriptomics data analysis are highly desired

• Exposure to neuroscience or immunology related projects

• Strong quantitative and analytical skills

• Strong presentations skills, including the ability to deliver complex quantitative analyses in a clear, concise, and actionable manner to extended team and small groups of key stakeholders

BENEFITS AND AMENITIES

• Competitive pay

• Travel, transportation and lodging support for eligible students

• Opportunity to connect with Abbvie leaders and scientists

• Exposure to cutting edge technologies and concepts

EQUAL EMPLOYMENT OPPORTUNITY

At AbbVie, we value bringing together individuals from diverse backgrounds to develop new and innovative solutions for patients. As an equal opportunity employer we do not discriminate on the basis of race, color, religion, national origin, age, sex (including pregnancy), physical or mental disability, medical condition, genetic information gender identity or expression, sexual orientation, marital status, protected veteran status, or any other legally protected characteristic.

AbbVie’s mission is to discover and deliver innovative medicines that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people’s lives across several key therapeutic areas: immunology, oncology, neuroscience, eye care, virology, women’s health and gastroenterology, in addition to products and services across its Allergan Aesthetics portfolio.