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Associate Scientist, High Throughput Screening

1859

Associate Scientist, High Throughput Screening

San Diego, CA
Full Time
Paid
  • Responsibilities

    COMPANY OVERVIEW:

    At 1859, we are creating a pico-scale HTS platform (pico-HTS) that enables us to test millions of small molecule potential medicines in a single day and at an exponentially lower cost point compared to conventional HTS. At scale, our technology has the potential to usher in the promise of precision medicine and democratize the medicine discovery process. At 1859, we are committed to scientific integrity, discipline, objectivity, and openness. Our team consists of very talented chemists, assay biologists, material scientists, integration engineers, automation specialists and informaticians working closely together to bring our screening technology to the world.

    We are comprised of high-performance engines, not cogs, and we invest in our people! Benefits include: paid holidays, PTO, a variety of medical plans, dental and vision insurance, a 401(k) plan, employee recognition awards, happy hours, company activities, and equity incentives. We are committed to training and career development for our people. Our goal is to provide a collaborative, data driven, productive and highly efficient company culture.

    If you have a passion for changing the world of new medicine discovery, we encourage you to apply!

    POSITION SUMMARY:

    In this laboratory-based position, the successful candidate will perform ultra-high throughput screening of small molecules pharmaceuticals. This includes system setup and troubleshooting, data analysis to support the identification of novel candidates for drug discovery and collaboration with the Engineering Team for the development of new hardware as part of technology development. Strong people skills and the ability to thrive in a team and goal driven environment are key attributes.

    This role will require close interactions with internal cross functional groups, including Engineering, Assay Development, Manufacturing, and Quality Assurance. You will give technical reports and presentations, document all aspects of projects, assist in QC/QA, and ensure that all documentation is ready for internal and external audits.

    KEY RESPONSIBILITIES:

    • Conducting daily system suitability checks on high throughput screening systems

    • Maintaining instruments in good working condition and performing troubleshooting analysis and maintenance as required

    • Assisting with instrument data analysis 

    • Supporting the development of new hardware as part of screening platform improvements 

    • Supporting lab operations and maintain general lab orderliness

    • Assisting in maintaining a safe working environment and operating in a safe manner

    REQUIREMENTS:

    • Bachelor’s degree or higher education; preferably in Biochemistry, Molecular Biology,  Engineering, or related field

    • 3+ years of experience in a biotechnology or pharmaceutical company

    • 3+ years of relevant working experience in either Manufacturing, Operations, Product Development or Clinical Labs

    • Participated in IVD product development or product V&V projects

    • Experienced in the creation of documents to describe processes and procedures for Manufacturing or Product Development

    • Working knowledge and experience with data analysis software, such as JMP, GraphPad or Prism 

    • Strong experience in problem solving skills, analytical thinking, and visionary skills

    • Outstanding written and oral communication skills

    • Strong interpersonal skills capable of working with a diverse group of people

    • Self-motivated, results oriented team player who leads by example, enthusiastically perseveres until ambitious goals are achieved, and reacts to situations quickly and decisively

    HIGHLY DESIRABLE:

    • Hands-on experience and knowledge of GMP, GDP guidelines

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    We take pride in fostering an environment where all team members are afforded the freedom to pursue their passion without regard to race, color, religion, national or ethnic origin, gender, sexual orientation, gender identity or expression, age, disability, veteran status or any other characteristics protected by law.