Job Description

We are seeking a highly motivated Associate Scientist with expertise in CRISPR gene editing and iPSC engineering to join our diabetes research team. This lab-based role will focus on advancing stem cell engineering and developing next-generation islet cell therapies. The ideal candidate will have hands-on experience in gene editing, molecular biology, and human iPSC culture and differentiation.

Key Responsibilities

• Perform CRISPR-based gene editing and optimize workflows for gRNA screening and delivery.
• Develop and characterize clonal gene-edited iPSC lines using flow cytometry, ddPCR, dPCR, and qPCR.
• Maintain routine iPSC culture, passaging, and media preparation.
• Execute directed differentiation of human iPSCs to pancreatic islets and assess drug substance quality (cell counts, viability, metabolite analysis).
• Conduct on-/off-target analysis via PCR and NGS workflows.
• Collaborate cross-functionally to support assay transfer from R&D to GMP environments.
• Maintain accurate experimental records, prepare reports, and contribute to SOP development.

Qualifications

Required:

• B.S. in Stem Cell Biology, Cell Biology, Bioengineering, or related field with 3–4 years of relevant industry experience; OR M.S. with 1–2 years experience.
• Hands-on experience with human iPSC culture and CRISPR gene editing.
• Proficiency in molecular biology techniques (PCR, ddPCR, dPCR, NGS).
• Familiarity with flow-based sorting and assay development (ELISA, luciferase assays).
• Strong organizational and communication skills.

Preferred:

• Experience in pancreatic islet differentiation and transitioning processes to GMP.
• Familiarity with electronic lab notebooks (ELN).
• Authorization to work in the United States indefinitely without restriction or sponsorship.

Additional Information

The position is Full Time, Monday-Friday, 8am-5pm with occasional weekends (on a rotational basis to support cell culture) . Candidates currently living within a commutable distance of Boston, MA are encouraged to apply.

What to Exp ect in the Hiring Process:

• 10-15 Minute Phone Interview with Region Recruiter
• 45-60 Minute Virtual Interview with Manager and/or Group Leader
• 45-60 Minute In-Person Meeting over Coffee for a Casual Discussion of the Role

What We Offer:

• Target pay range: $37-41/hr
• Excellent full-time benefits including comprehensive medical coverage, dental, and vision options
• Life and disability insurance
• 401(k) with company match
• Paid vacation and holidays
• Yearly goal-based bonus & eligibility for merit-based increases

Ready to make an impact in cutting-edge cell therapy?
Apply today and join Eurofins PSS in advancing CRISPR gene editing and iPSC engineering for next-generation diabetes treatments.

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.