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Principal Scientist - Assay Development

DermTech

Principal Scientist - Assay Development

San Diego, CA
Full Time
Paid
  • Responsibilities

    ABOUT US:

    At DermTech, we believe there's a better way to assess skin conditions, and we're using technology, innovation, and data to fundamentally change the way the world practices dermatology. DermTech has developed technology that assesses the skin at the molecular level, i.e., RNA and DNA, so that signs of skin cancer are detected far earlier, unnecessary biopsies are avoided, and healthcare providers can enable optimized treatment plans, and customize skincare plans to a person's unique skin molecular makeup. A method that is centered around DermTech's patented smart sticker, which collects tissue from your skin's surface easily, accurately, and painlessly. The skin cells are assessed in DermTech's state-of-the-art laboratory which analyzes that tissue at the genomic level. We call this practice “precision dermatology”, a truly new era in disease detection. By pushing the boundaries in areas like cancer detection and patient care, our technology can truly change the world. And we're seeking team members with the vision, passion, and creativity to do the same.

    FUNCTIONAL DESCRIPTION:

    DermTech is seeking an experienced and motivated Principal Scientist to join our research team in San Diego, California to drive biomarker research, discovery, and validation in dermatological diseases. The successful candidate will join a research team that combines cutting-edge proteomic and genomic approaches to interrogate and characterize molecular pathways involved in the pathogenesis of dermatological disease. Specifically, the candidate will work as a member of a multi-disciplinary team using internal and publicly available data to identify novel biomarkers as well as personalized medicine strategies. The successful candidate will benefit from daily interaction with highly accomplished scientists with whom they will collaborate. The position offers a unique opportunity for a talented scientist to work in a dynamic and innovative environment and to develop their career at the interface of precision and personalized dermatology.

    PRIMARY DUTIES & RESPONSIBILITIES:

    • Participate in disease focused translational biomarker programs and clinical biomarker assessment.
    • Develop new assays aligned with the company's goal on platforms including multiplexed RT-qPCR, Next Generation Sequencing (including RNA seq platforms), DNA methylation, and/or Mass Spectrometry (MassArray).
    • Recognize problems, understand and troubleshoot assays in an individual and team setting.
    • Drive implementation of solutions and deliver test results
    • Collaborate with internal and external partners to identify potential predictive, prognostic, pharmacodynamic, and diagnostic biomarkers.
    • Test candidate biomarkers using a combination of assay technology platforms.
    • Manage samples from experiments, collaborations, and clinical trials.
    • Collaborate with interdisciplinary teams to drive data analysis, integration, and application across various ‘omics platforms.
    • Foster innovation and new product development in collaboration with cutting edge data science and computational biology teams.
    • Translate insight from model systems into predictors and classifiers of therapeutic response and prognosis in clinical diseases.
    • Contribute to presentation and reporting of methods, results and conclusions in scientific conferences and peer-reviewed literature.

    EDUCATION/EXPERIENCE/SKILLS:

    • Doctorate (PhD) with relevant experience in Immunology, Molecular Biology, Genetics, Systems Biology, Computational Biology, or related field is preferred.
    • Experience in Molecular Biology, multiple omic data platforms, and emerging technologies, especially in terms of measuring gene expression.
    • Documented experience in developing molecular tests from design to commercialization.
    • Motivated, innovative and strong team player able to function with a high degree of independence.
    • Outcome-oriented and attentive to details with strong analytical skills.
    • Strong interpersonal and communication skills and record of scientific achievement through peer-reviewed publications, invited oral presentations, or patents.

    ADDITIONAL INFORMATION: An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable. DermTech is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at DermTech via-email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of DermTech. No fee will be paid in the event the candidate is hired by DermTech as a result of the referral or through other means.