ABOUT DERMTECH:

At DermTech, we believe there's a better way to treat your skin, and we're using technology, innovation, and data to fundamentally change the way the world practices dermatology. We have developed technology that assesses your skin at the RNA and DNA level, so we can see signs of skin cancer far earlier, reduce the need for surgery, enable optimized treatment plans, and customize skincare plans to your skin's unique molecular makeup. We call this practice “precision dermatology” and we believe it truly is a new era in disease detection. A method that is not just better, but different. One centered around our patented smart sticker, which collects tissue from your skin's surface easily, accurately, and painlessly, and our state-of-the-art Gene Lab, which analyzes that tissue at the genomic level using a proprietary gene analysis system. By pushing the boundaries of areas like cancer detection and patient care, we truly believe our technology can change the world. And we're seeking team members with the vision, passion, and creativity to do the same.

GENERAL DESCRIPTION:  

DermTech is seeking a PRINCIPAL BIOINFORMATICS SCIENTIST to join our Research and Development team in San Diego, California to drive biomarker research and discovery.  The successful candidate will collaborate with the bioinformatics and product development teams to mine internal and publicly available genomic and proteomic datasets.  The candidate will be responsible for processing large next-generation sequencing (NGS) datasets and applying machine-learning (ML) approaches to combine multi-factorial clinical/translational data to identify biomarkers capable of diagnosing disease and potentially predicting therapeutic response.  This position offers a unique opportunity for a talented Principal Bioinformatics Scientist to work at the cutting edge of precision dermatology and personalized medicine.

PRIMARY DUTIES & RESPONSIBILITIES:

• Develop computational methods for integrative analysis and visualization of large multi-omic datasets, such as transcriptomics or DNA variants, and correlation with clinical data.
• Collaborate with interdisciplinary teams to drive data analysis, integration, and application across various ‘omics platforms.
• Work across the organization to offer bioinformatics and/or biostatistics support.
• Develop pipelines and test algorithms to optimize the analysis of NGS data produced from samples collected by our smart sticker platform.
• Search large complex datasets to identify predictive features and combine these in ML algorithms to predict disease status.
• Participate in disease-focused translational biomarker programs and clinical biomarker assessment.

QUALIFICATIONS:

• Ph.D. in computational biology, bioinformatics, genomics, systems biology, statistical genetics, data science, or a closely related field.
• Post-Ph.D. experience as a postdoc in a related field; 1+ years of industry experience preferred
• Strong interpersonal and communication skills
• A track record of peer-reviewed scientific publications in leading scientific journals.
• Experience with one or more of the following:
  • Genome-wide NGS experiments such as RNA-seq/WGS or their targeted AmpliSeq counterparts
  • Algorithms or machine-learning models that combine multiple data types
  • The integrative analysis of multiple ‘omics datatypes
  • Clinical trial data or real-world evidence data
  • Biomedical research data; in particular, relating to oncology or autoimmune diseases
  • Illumina's cloud NGS analysis platforms, such as BaseSpace and ICA
  • Working closely with wet-lab scientists to optimize NGS library contrition methods
  • Working closely with product development teams to bring products to the market
  • Design and power calculations for clinical studies and biomarker discovery
  • Strong interpersonal and communication skills as well as a track record of peer-reviewed scientific publications in leading scientific journals.

ADDITIONAL INFORMATION:

An Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability. If you are an individual with a disability and would like to request a reasonable accommodation as part of the employment selection process, please contact Talent Acquisition. DermTech is not accepting unsolicited assistance from search firms for this employment opportunity. All resumes submitted by search firms to any employee at DermTech via email, the Internet, or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of DermTech. No fee will be paid in the event the candidate is hired by DermTech as a result of the referral or through other means.