ABOUT THE TENSIXTEEN BIO

TenSixteen is the first company to leverage somatic mosaicism and clonal hematopoiesis of indeterminate potential (CHIP) to discover and develop novel therapeutics to treat age-related diseases. We are a precision platform therapeutics company utilizing novel genomic biology across multiple disease areas. TenSixteen was conceived around the promise of leveraging unique data assets and capabilities to drive discovery and novel clinical development paradigms, and we are building a genomics and data science platform that will enable data integration and generation to support these efforts. We aim to transform the future of precision medicine in complex diseases.

ROLE

We are looking for a stem cell biologist familiar with hematopoiesis to join our multidisciplinary team to translate targets and pathways of interest derived through multiomic analyses. This individual will lead the development of novel in vitro and in vivo pre-clinical models to explore hematopoietic systems targeting, in both malignant and non-malignant settings. In addition, this individual can play a key role in collaborating with leading labs and institutions. This position is located at our laboratory headquarters in the San Francisco Bay Area.

RESPONSIBILITIES

• Design, execute, and analyze in vivo and in vitro experiments of hematopoietic clonal dynamics and disease
• Ideal candidates can readily interface with colleagues to facilitate bone marrow transplantation, CRISPR genetic modification, and single cell platform analytics in multiple pre-clinical disease models
• Evaluate literature for existing and novel approaches to modulate the hematopoietic stem cell system
• Collaborate and maintain communication with other functions in the company, especially with colleagues from genomics and bioinformatics

REQUIRED QUALIFICATIONS

• Ph.D training in the life sciences or M.D. with extensive basic science research experience
• Particularly interested in candidates with significant experience in flow cytometry, including panel design and sorting
• Familiarity with cell culture, cloning strategies, and viral vectors
• Experience in managing a research team in academia and/or industry
• Strong self-motivation and ability to pivot to new directions as data develops in this novel multidisciplinary space

WE ARE AN EQUAL OPPORTUNITY EMPLOYER. WE THRIVE ON DIVERSITY AND COLLABORATION.