Job Description
We are seeking an associate scientist/scientist to join the Smart Lab within Drug Product Design and Supply.
The successful candidate will develop and deploy automation and technology processes for pharmaceutical drug candidates in a laboratory setting.
Position Responsibilities
- The successful candidate will help develop laboratory automation solutions for drug product development applications as part of a multi-disciplinary team.
- Assist with design and testing of modular hardware to facilitate data-rich experimentation.
- Partner with research scientists and engineers on suitable experimentation to deliver DPDS workflows for solid dosage form development.
- Collaborate with colleagues to define and implement crystallization, polymorph, and salt screening activities according to project timelines.
- Conduct solid state physical and chemical characterization of small molecules of pharmaceutical relevance. This includes solid state characterization (e.g., spectroscopy, X-ray powder diffraction, thermal analysis).
- Analysis of powder samples for key physical properties (such as particle size distribution, bulk density, true density, powder flow, particle shape)
- Development and characterization of prototype formulations for pharmaceutical small molecules on small scale with small amounts of material (mg) on rapid timelines.
- Measurement of key active compound and formulation properties (such as crystallinity, solubility, dissolution, etc.)
- Assessment of the performance of prototype formulations using in-vitro tests (dissolution, precipitation, etc.).
- Rapid and detailed documentation of experimental procedures and data in electronic laboratory notebooks.