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BCC - Part Time Instructor, Biology

NGM Biopharmaceuticals

BCC - Part Time Instructor, Biology

South San Francisco, CA
Paid
  • Responsibilities

    NGM Biopharmaceuticals, Inc. is a clinical stage biotech company dedicated to discovering and developing the next generation of medicines for the treatment of serious diseases. Our experienced scientific team has joined forces with an impressive group of industry professionals, Nobel Laureates and other distinguished researchers to form a company where innovation and cutting-edge science has provided the foundation for a robust drug discovery engine. To date, NGM Bio has generated a pipeline of seven drug candidates in various stages of development targeting liver, metabolic and ophthalmic diseases and cancer. The most advanced drug candidate, NGM282, is entering Phase 2b clinical studies in non-alcoholic steatohepatitis (NASH). NGM’s strategic collaboration with Merck, which was extended to March 2022, will continue to provide us with the resources and flexibility to pursue our ambitious R&D goals and further extend our pipeline of novel drug candidates.

    NGM currently has an opening for a highly motivated individual to join our CMC team. The team is responsible for progressing NGM’s cutting edge science derived protein therapeutics from the research lab to the clinic. The position in Downstream Process Development will carry out downstream technical activities to support both early stage and late stage clinical development projects. The position requires knowledge and hands-on experience of lab-based purification development. The successful candidate shall be independent, team oriented, and efficient in multitasking.

    Required Skills

    • Design and execute experiments to support downstream process development including small-scale and preparative chromatography, filtration, ultrafiltration/diafiltration (UF/DF), and protein refolding. Clearly document experimental results in electronic lab notebook
    • Manage and analyze process development experimental results; troubleshoot experiments as needed; communicate results and recommendations.
    • Review protocols, technical reports, batch records, SOPs, and regulatory submissions.
    • Support deviation investigations to resolve downstream related issues.
    • Ability to work collaboratively with members from CMC, QA, and Regulatory Affairs to achieve project goals and timelines.

    Required Experience

    EDUCATION REQUIREMENTS:

    • Candidates with Sc. or B.Sc degree will be considered with more than 2 years’ relevant industry experience.
    • Ph.D. in Chemical Engineering, Biotechnology or equivalent disciplines will also be considered with 0-3 years’ relevant industry experience. Job level may be adjusted based on experience.

    DESIRED EXPERIENCE:

    • Knowledge of downstream unit operation principles and experience with chromatography, filtration, and UF/DF equipment is required.
    • Knowledge and hands-on experience with analytical techniques such as UV-vis spectroscopy, HPLC, SDS-PAGE are desired.
    • Excellent written and oral communication skills
    • Prior experience effectively interacting with CMOs is a plus
    • Ability to work in a fast-paced environment, to multitask, and manage multiple projects
    • Ability to independently make decisions based on data, scientific knowledge and sound judgement

    NGM offers a creative, collaborative, highly challenging scientific environment.

    Contract term length 3 months, with possibility to extend.

    Interested applicants should apply through the NGM Biopharmaceuticals website: http://www.ngmbio.com/careers/#SilkroadFrame

  • Qualifications
    • Design and execute experiments to support downstream process development including small-scale and preparative chromatography, filtration, ultrafiltration/diafiltration (UF/DF), and protein refolding. Clearly document experimental results in electronic lab notebook
    • Manage and analyze process development experimental results; troubleshoot experiments as needed; communicate results and recommendations.
    • Review protocols, technical reports, batch records, SOPs, and regulatory submissions.
    • Support deviation investigations to resolve downstream related issues.
    • Ability to work collaboratively with members from CMC, QA, and Regulatory Affairs to achieve project goals and timelines.