POSITION OVERVIEW:

Reporting to the Director of Research, the Radiochemist Scientist will participate as a key member of the ImaginAb Research Team by taking responsibility for running radiolabeling experiments of antibody fragments and perform all necessary characterizations. This role will optimize new conjugations with metal chelators and develop QC assays across multiple projects against different cancer targets. Draft technical reports and SOPs, and support transfer of such processes to external collaborators. This position is part of a cross functional team and supports different activities such as production of radiolabeled samples for in-vivo experiments, as well as scale-up conjugation reactions for process development.

ESSENTIAL JOB FUNCTIONS:

• Radiolabeling with radioisotopes for imaging and radiotherapy

• Preparation of protein / small molecule conjugates, such as antibodies, minibodies or cys-diabodies, with metal chelators or fluorescence dyes

• Conjugation process development to support scale-up production and manufacturing development.

• Hands-on experience handling radioactive samples, and knowledge of radiation safety regulations

• Conjugation process improvement for identification of novel chelators

• Preparation and testing of other chemistry related reagents and solutions

• Characterization and QC assays of antibody conjugates including SE-HPLC, RP-HPLC, icIEF, SDS-PAGE, UV-Vis, ELISA, flow cytometry

• Writing batch records, SOPs, and technical development reports

• Presentation of work at internal meeting

• Assist with process transfers to CMOs or external partners

• Document and data management

• Contribute to drafting publications and posters as needed

• Other responsibilities as assigned

REQUIRED EDUCATION AND EXPERIENCE:

• Master’s degree in chemistry, biochemistry or related discipline with 2+ years of industrial experience in small biotech or pharma company, OR bachelor’s degree in biochemistry or related discipline with 5+ years of experience in industry
• Strong analytical skills with ability to resolve problems and undertake proper corrective steps
• Demonstrated superior communication and collaboration skills
• Strong organizational, planning and follow-through skills
• Proactive work ethic and attention to details
• Commitment to a rigorous data documentation and data recording
• Commitment to a rigorous adherence to strict safety policies
• Ability to work well under pressure and within deadlines
• Work independently with minimal supervision, but also flexible to accept external inputs and comfortable working in a small team

PHYSICAL AND MENTAL REQUIREMENTS:

• The mental and physical demands, and work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
• Remaining in a stationary position, often sitting for prolonged periods in an indoor office environment.
• Must be able to access and navigate throughout various offices.
• Communicating with others to exchange information and perform duties: talking/hearing/writing/typing.
• Ability to read materials in paper format and on a computer screen.
• Repeating motions that may include the wrists, hands and/or fingers.
• Specific vision abilities required by this job include close vision and ability to adjust focus.
• Ability to read, analyze, and interpret general professional journals, technical procedures and governmental regulations.
• Ability to write reports, business correspondence, and procedural materials.
• Ability to define problems, collect data, establish facts, and draw valid conclusions.
• Low to Moderate noise levels consistent with an office environment.

WORK ENVIRONMENT:

• Must be able to work in a lab setting with exposure to biohazards.
• The worker is subject to inside environmental conditions: Protection from weather conditions but not necessarily from temperature changes.
• There are conditions, equipment and materials present which require proper handling to ensure safety.

SALARY AND BENEFITS

Salary commensurate with experience and robust benefits package offered.  Inclusive and great team environment.  Resumes through search firms will not be accepted.  

ABOUT IMAGINAB

ImaginAb are world leaders in the development of immunoPET and our late-stage imaging agent is utilized in a rapidly increasing number of trials.  Alongside ImaginAb sponsored studies, we work with some of the world’s largest pharmaceutical companies and most innovative biotech’s to study CD8+ cell distribution in patients prior to and during immunotherapy, to better understand the action of this critical class of cancer medicine.  

Join us as we reimagine a new vision and approach towards immune-oncology patient care paths. Explore more about who we are, how we innovate for tomorrow, and why partnering with us will help to challenge, create, and transform patient care at https://imaginab.com/ 

ImaginAb, Inc. is an equal opportunity employer, we evaluate qualified applicants without regard to race, color, religion, sex, national origin, disability, veteran status, or any other legally protected characteristics.