Job Description
We are seeking for hands-on immunoassay developers for a new Analyte Detection Business Unit. If you have designed assays from scratch, selected and screened reagent pairs, and solved real development problems across ELISA, MSD, TR-FRET, AlphaLISA, or related formats, we want to hear from you. Here’s what you’ll do:
_ Laboratory Execution & Technical Support_
- Design and execute bioconjugation strategies for labeling antibodies and other proteins with donor/acceptor fluorophores (NHS-ester, maleimide, and related chemistries); optimize reaction conditions, purification, and labeling efficiency from first principles
- Develop homogeneous immunoassays (TR-FRET, HTRF, AlphaLISA, MSD, and/or ELISA) for analyte detection; own the full development cycle from reagent selection and antibody pairing through format optimization and matrix validation
- Lead independent antibody screening campaigns to identify optimal capture/detection pairs; apply structured DOE approaches to optimize reagent concentrations, buffer formulations, and assay window
- Conduct routine assay validation experiments, including precision, accuracy, linearity, and range determination
- Prepare biological samples, reagents, and buffers according to SOPs
- Operate and maintain laboratory equipment, including plate readers, liquid handlers, and analytical instruments
- Independently diagnose and resolve assay performance failures; apply root-cause analysis to reagent, buffer, and instrument variables and propose data-driven corrective actions
- Support antibody screening and characterization activities
- Assist with benchmarking studies comparing assay performance to competitor products
_ Data Management & Documentation_
- Maintain detailed, accurate, and organized laboratory notebooks documenting all experimental procedures and observations
- Analyze experimental data using GraphPad Prism, Excel, or similar software
- Generate clear data summaries, graphs, and tables for internal reports and presentations
- Contribute to technical reports and validation documents
- Assist in drafting sections of SOPs and user manual protocols
- Ensure all documentation meets company quality standards and regulatory requirements
_ Collaboration & Learning_
- Work collaboratively with Senior Scientist and other team members to support project timelines
- Participate in team meetings and provide updates on experimental progress
- Communicate experimental results and technical challenges effectively to the supervisor
- Actively seek learning opportunities to develop technical skills in bioconjugation and immunoassay development
- Support cross-functional activities with Manufacturing, Quality, and Marketing teams as needed
- Participate in training programs to enhance scientific and professional development
_ Compliance & Safety_
- Adhere to all site employee health and safety (EHS) and IT security requirements
- Demonstrate and promote the company vision and values
- Maintain regular attendance and punctuality
- Conduct all activities in a safe and efficient manner
- Perform other duties as assigned
- Meet project deadlines and adjust work hours as needed to support team objectives