Job Description

• Candidate will be working onsite
• Experience must be within Pharma or Biotech Client is seeking a Senior Associate Scientist responsible for all aspects of production cell line development in support of advancing the client pre-clinical pipeline as part of the Drug Substance Process Development organization. Responsibilities include, but are not limited to: • Design, execute and analyze mammalian cell culture experiments including transfection, selection, single cell cloning, passaging, screening, banking, and characterization • Analyze and interpret data, maintain laboratory notebooks, and generate written reports • Generate relevant data towards authoring of regulatory submissions, publications, and patent applications • Communicate project updates, solve complex technical problems, participate and present scientific data in meetings • Evaluate and develop innovative technologies to improve expression, accelerate timelines, and improve efficiency • Work closely in a team environment, collaborating with various colleagues in process development, discovery, as well as interact with regulatory and quality experts in support of global regulatory filings Preferred qualifications: • Previous hands on experience in cell culture with a focus on recombinant protein production in CHO cells • Experience with DNA cloning, vector construction and design, advanced molecular biology techniques, and optimizing gene expression constructs to promote desired gene expression characteristics (high expression, stoichiometry, chain ratio balance etc) • Strong scientific understanding of recombinant protein expression, cell line and gene editing technologies as well as the ability to explore and develop new technologies and approaches • Understanding of all aspects in cell line development, bioprocess development and manufacturing of biotherapeutics • Advanced scientific/technical reading/writing skills, advanced analysis skills, ability to collaborate and work in team environment. • Ability to work independently and as part of a team, self-motivation, adaptability, and a positive attitude

Qualifications

BASIC QUALIFICATIONS: PHARMA/BIOTECH EXPERIENCE PhD in Biological Sciences, Molecular Biology, Biochemical Engineering or related life science discipline OR Relevant Master’s degree + 3 years industrial experience OR Bachelor’s degree + 5 years of industrial experience  

Additional Information

TOP 3 MUST HAVE SKILL SETS:

• Previous hands on experience in cell culture with a focus on recombinant protein production in CHO cells • Experience with DNA cloning, vector construction and design, advanced molecular biology techniques, and optimizing gene expression constructs to promote desired gene expression characteristics (high expression, stoichiometry, chain ratio balance etc) • Understanding of all aspects in cell line development, bioprocess development and manufacturing of biotherapeutics