Job Description
SCIENTIST/SR SCIENTIST - ANALYTICAL DEVELOPMENT
LOCATION: SAN DIEGO, CA
PAY RATE: $120-150K
POSITION SUMMARY:
This position will be responsible for leading and executing the analytical development strategy for our preclinical and clinical scale candidates in development. The candidate will be expected to work in collaboration with our internal research group, process development group, as well as our external manufacturing and analytical development partners to identify, develop, and implement appropriate analytical methods to characterize AAV based gene therapy products across our pipeline. The successful candidate will be a subject matter expert in contemporary analytical methods used to support biological products and will be required to identify and mitigate quality risks to enable successful product development. The successful candidate will also contribute to the preparation of quality sections of INDs and other regulatory documents. As an early stage startup this position will require flexibility, creativity and a can-do attitude to enable efficient execution of company objectives. The level of the position will be commensurate with experience.
KEY RESPONSIBILITIES:
KEY REQUIREMENTS
· Degree in Biochemistry, Cell and Molecular Biology, Genetics or related discipline. Scientist level applicants should have a PhD in Biochemistry OR a Master’s degree with >5 years of relevant experience; Senior Scientist level applicants should have a PhD, a post-doc, and >2 years of relevant experience
· Hands-on experience optimizing and executing AAV testing and characterization techniques such as: ddPCR, qPCR, SDS-PAGE, ELISA, Western blots, Capillary Electrophoresis, Analytical Ultracentrifugation, HPLC and cell- based potency and infectivity assays
· Experience working with viral vectors for gene therapy and with contract research or manufacturing organizations is ideal