_Sanford Burnham Prebys is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease, and advancing scientific discoveries to profoundly impact human health. _

The D'Angelo laboratory has a POSTDOCTORAL ASSOCIATE position available in the areas of immune regulation, skeletal muscle and cancer.

The main focus of the D'Angelo's laboratory is to study the role of Nuclear Pore Complexes, the multi-protein channels that connect the nucleus with the cytoplasm. Using a combination of cell biology, imaging and animals models the lab seeks to understand how nuclear pores regulate the physiology of different tissues and to establish how alterations in the function of these structures contribute to cellular malfunction and disease. The D’Angelo laboratory also has a strong emphasis in the translation of basic discoveries into clinical applications.

The Postdoc Associate will focus on increasing our understanding of the regulation of tissue homeostasis by nuclear pore complexes and other components of the nuclear transport machinery. The successful candidate will be part of a highly collaborative research team and will have the opportunity to work with advanced techniques in molecular and cellular biology, genetics, imaging, and models of disease. The candidate is expected to play a key role in dissecting the mechanisms of function of components of the nuclear transport system and in establishing their potential therapeutic implications for muscle disease and cancer. Some studies may involve the identification of novel drug targets, the development of high throughput screening assays and small molecule screening campaigns.

TO APPLY: Interested candidates should apply online to the SBP career site by submitting one PDF document with a cover letter, CV, references and list of any publications or accomplishments. 

VIEW THESE LINKS ON THE CURRENT RESEARCH IN THE D'ANGELO LAB: 

KILLING CANCER BY BLOCKING CELL DOORS

SCIENTISTS KILL CANCER CELLS BY “SHUTTING THE DOOR” TO THE NUCLEUS

CELEBRATING THE NEXT GENERATION OF BIOMEDICAL TRAILBLAZERS AT THE 19TH ANNUAL FISHMAN FUND AWARDS

Primary Responsibilities

• Independently designs and performs experiments and procedures with high degree of complexity, demonstrating increasing expertise with a wide range of techniques
• Demonstrates flexibility in adapting methods and skills according to evolving project priorities
• Provides independent experimental design and planning
• Analyzes and interprets data from different sources and draw relevant conclusions
• Presents results at internal and external meetings
• Accurately documents experiments
• Contributes to writing of reports and manuscripts with increasing responsibility over time
• Works collaboratively across lab functions and trains other junior lab staff as needed

 

Required Skills Required Experience

• Ph.D. degree in Science is required
• Previous Postdoc training is not required.

 

Knowledge, Skills and/or Abilities

• Demonstrated knowledge in relevant specialized disciplines
• The ability to work independently and to handle multiple projects and deadlines
• Ability to work in an interactive and collaborative team
• Excellent presentation, verbal, and written communication skills
• Possess strong attention to detail, analytical, time management, organizational, and interpersonal skills
• Embody the Institute's core values of Commitment, Collaboration, Communication, Community and Compassion

The scientists at Sanford Burnham Prebys Medical Discovery Institute are making research breakthroughs in cancer, neuroscience, immunology, and children's disease. We are also at the forefront of finding solutions for emerging health threats such as COVID-19, where we are working to identify drugs that may help millions of people. During our more than 40 year history, we have established an NCI-designated Cancer Center, designed one of the most sophisticated drug discovery centers in the nonprofit world, and created global collaborations that are leading to preventions, treatments and cures to improve human health. 

Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law.  For additional information about your rights as an applicant, click HERE.

REQUIRED EDUCATION AND EXPERIENCE

Degree issuing institution and or program must be accredited by an entity recognized by the U.S.

Department of Education

1. Doctor of Medicine or Doctor of Osteopathic Medicine from a school in the United States or,
2. Doctor of Medicine or equivalent degree from a foreign medical school that provided

education and medical knowledge substantially equivalent to accredited schools in the United

States as established by:

1. The National Committee on Foreign Medical Education and Accreditation

(NCFMEA) and

1. Permanent certification by the Educational Commission for Foreign Medical

Graduates (ECFMG).

3. A minimum of six years post residency experience providing direct patient care as a board

certified physician in Family Medicine or Pediatrics.

A minimum of three years’ experience in the provision of clinical supervision and leadership to

other medical professionals and ancillary clinic staff.

 

ATTRIBUTES AND PROFESSIONAL QUALITIES

1. Strong oral and written communication skills.
2. Strong leadership skills.
3. Excellent interpersonal skills.
4. Critical thinking skills
5. Cultural competency.
6. Integrity and honesty.
7. Verbal and written proficiency in Spanish (preferred, not required).
8. Experience in a detention/correctional or residential healthcare setting (preferred, not

required).

 

REQURED LICENSURE / CERTIFICATION

1. Current, full, and unrestricted license to practice medicine in the state in which the duty

station is located. The license must be maintained in a permanent, full, and unrestricted status

during the term of employment. Any changes to licensure must be reported to employer

immediately.

2. Current Board certification in Family Medicine or Pediatrics by the American Board of

Medical Specialties (ABMS) or American Osteopathic Association (AOA) approved board

All other board certified candidates must be presented to the IHSC Medical Director for

concurrence.

3. This position requires privileging by IHSC.
4. Maintains BLS for Healthcare Providers® certification through the American Heart

Association.

 

REQUIRED KNOWLEDGE, SKILLS, AND ABILITIES

1. Expert knowledge of the current standards of practice in clinical medicine.
2. Ability to serve proficiently as a clinical expert, providing technical assistance and

consultation to clinic medical staff.

3. Ability and proficiency to properly use equipment, materials and supplies in simple

diagnostic and treatment procedures.

4. Ability to provide input for congressional inquiries and to effectively communicate with

Federal Agencies and other organizations as indicated.

5. Mastery of managerial and administrative practices, to include expertise in routine

management of ambulatory clinic functioning and responsibilities.

6. High degree of independence, initiative, clinical judgment, and follow-through on a wide

range of sensitive, complex, and clinical issues.

7. Teaching experience acknowledging a level of expertise and capacity for developing and

accessing clinical educational programs.

8. Knowledge of issues confronting the healthcare delivery system, including specific problems

and concerns of special population groups.

9. Knowledge of program policies and guidelines, and operating procedures relating to

healthcare delivery systems.

1. Knowledge of organizations and responsibilities of all levels of government operations.
2. Ability to work in a multi-cultural and multi-lingual environment.
3. Ability to utilize telephonic interpreter/translation services to complete assigned duties if not

fluent in a language the patient understands.

3. Ability to adapt to sudden changes in schedules and flexibility in work requirements.
4. Ability to communicate proficiently in English (verbal and written) in order to develop

positive rapport with patients, co-workers and other stakeholders.

5. Ability to establish and maintain positive working relationships in a multidisciplinary

environment.

6. Ability to navigate in an electronic work environment including electronic health records,

web based training and communications.

7. Moderate proficiency in, common Microsoft Office programs, specifically Microsoft Word,

Excel, Outlook and SharePoint.

8. Knowledge of regulations (HIPAA/Privacy Act) regarding the confidentiality of patient

medical records and information as well as Personally Identifiable Information (PII).

 

DUTY HOURS / ON-CALL REQUIREMENTS

IHSC operates 24/7/365 you may be required to respond telephonically during emergency call

back roster activation.

1. This full time position is required to provide rotational on-call coverage and may need to

return to the facility during non-core hours to provide care.

2. This full time position is required to be available telephonically and/or to report to the facility

during non-core hours.

 

SECURITY REQUIREMENTS

1. The Department of Homeland Security’s Personnel Security Unit (PSU) must render a

Preliminary Favorable Fitness Determination to be considered a qualified candidate.

2. A Complete Favorable Fitness Determination must be rendered by PSU upon completion of

initial and subsequent background investigations to meet the requirements of this position.

 

PHYSICAL DEMANDS:

1. Required to walk unaided at a normal pace for up to 10 minutes and maintain balance.
2. Required to respond to any medical emergency within 4 minutes, where a fast walk or jog

may be necessary to provide assistance.

3. Required to perform CPR/emergency care standing or kneeling.
4. Must have the ability to assist sick, injured or aging residents or staff exiting the building

during an emergency (may require lifting, dragging, wheeling or carrying someone who weighs

significantly more than self).

5. Must be able to see, hear and smell with or without the use of aides if necessary

(exceptions on a case by case basis).

6. Must easily alternate between kneeling and standing.
7. Must be able to lift, push, or carry 30 pounds.
8. Must perform the duties in a stressful and often austere environment without physical

limitations.

9. Must be capable of standing on hard services (cement floors) for long periods of time.

 

SUPERVISORY CONTROLS:

This is a contract position and supervisory controls will be set forth by the Contractor . Technical

oversight will be provided by the Government Technical Monitor (GTM).