Scientist I - Downstream Process Development
Company Overview Salubris Biotherapeutics, Inc. (or SalubrisBio) is a science-driven biotechnology company dedicated to the discovery and global development of novel antibody therapeutics for the treatment of cancer, cardiovascular and metabolic diseases. We strive to develop novel therapeutic molecules which provide clinically meaningful improvements in disease burden and quality of life to patients with significant medical needs. Role Summary
SalubrisBio is seeking highly motivated full-time Scientist – Downstream Process Development with exceptional ability to develop and transfer downstream process from development laboratory to clinical manufacturing facilities for antibody drug product production. The candidate shall have strong ability in downstream process development and is expected to work in a fast paced, dynamic and changing start-up environment with high degree of self-motivation.
Job Responsibilities:
· Develop robust and scalable downstream processes at laboratory scale for the purification of antibodies or antibody-based therapeutic proteins with chromatography (affinity, IEX and/or HIC, etc.), using DOE based approaches.
· Support scale-up of downstream processes and technology transfer to cGMP manufacturing facilities for clinical material production; work with cGMP manufacturing team to generate and review SOPs and batch record for traceability.
· Perform routine bench-work under limited supervision, effectively prioritize responsibilities and complete assignments in a timely manner.
· Able to analyze, interpret, and present results to project teams and write technical reports.
· Support equipment maintenance and calibration.
· Train junior scientists as needed.
Qualifications:
· PhD in Biochemical/Chemical Engineering or related scientific disciplines with 0 – 1 years of relevant experience, MS with 3+ or BS with 5+
· Industry experience in process development for therapeutic protein purification with standard downstream purification techniques including depth filtration, FPLC and TFF is preferred.
· Strong verbal and written communication skills, ability to work on multiple projects simultaneously and attention to details, good time management skills and self-motivation.
· Ability to work independently as well as in a highly collaborative/team-oriented R&D environment.
SalubrisBio is an Equal Employment Opportunity employer. Benefits include:
· Hybrid work opportunities
· Competitive pay
· 401(k) with company matching.
· Medical, dental and vision insurance
· Flexible Spending Accounts (FSA) and Health saving Account (HSA)
· Free Life insurance
· Generous Paid time off
· Tuition reimbursement
· Opportunities to learn upstream and analytics related CMC work
· Cell phone stipend
Flexible work from home options available.