SBP is a preeminent, independent biomedical research institute dedicated to understanding human biology and disease, and advancing scientific discoveries to profoundly impact human health. For over 40 years, our research has produced breakthroughs in cancer, neuroscience, immunology and children’s diseases, and is anchored by our NCI-designated cancer center and advanced drug discovery capabilities.

Currently the laboratory of Crystal Zhao is digging deeper into the molecular mechanisms through which m6A regulates RNA stability. They are also investigating how m6A regulates mESC ground state and whether m6A plays a role in mESC differentiation. Recently the lab identified a protein complex that governs m6A formation. Significantly they discovered that m6A shortens the half-life of a subset of mRNAs, including mRNAs encoding pro-differentiation genes.

The RESEARCH ASSISTANT I will be working in the Zhao lab and will be involved in cell culture and biochemical work, and other related duties and tasks as assigned. The Research Assistant will be multi-tasking and work in a fast-paced environment. The most critical requirement of the candidate is to be fully capable at benchwork – learning new technologies as well as applying existing knowledge to procedures. In addition, the candidate is expected to manage a project under limited supervision. 

Primary Responsibilities

• Act under limited supervision to determine methods and procedures on new assignment and receive directions from supervisor when needed
• Keep written record of experiments and data organization
• Troubleshoot problems and develops solutions to technical problems of moderate to high scope using independent thinking, literature, and colleagues as resources to solve problems
• Provide interpretation and analysis of results
• Maintain various reagent collections, and inventories
• Order lab supplies, as needed

Required Skills Required Experience

• Bachelor's degree in biological science, chemistry or related field or an equivalent combination of education, training and experience from which comparable knowledge, skills and abilities have been attained
• Prior lab experience is a plus 
• Candidates with a strong background in mammalian cell culture and molecular biology are preferred

Knowledge, Skills and Abilities

• Work independently as well as in a team environment
• Be responsible and have strong time management skills
• Able to analyze and resolve issues of moderate complexity
• Possess strong attention to detail and organizational skills
• Demonstrate professional communication and interpersonal skills
• Professional proficiency in Microsoft Office
• Embody the Institute’s core values of Commitment, Collaboration, Communication, Community and Compassion

Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity employer – M/F/Veteran/Disability – committed to the hiring, advancement and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law. For additional information about your rights as an applicant, click HERE_._