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Dr. Crystal Zhao laboratory studies the functions of (i) RNA epigenetics and (ii) long noncoding RNAs in stem cells and in cancer biology.

The Zhao laboratory has a POSTDOCTORAL ASSOCIATE position immediately available. We are looking for a highly motivated recent Ph.D. with strong training in epigenetics and/or stem cell biology to lead projects on the role of RNA epigenetics in cancer stem cells. RNA epigenetics, defined as a post-transcriptional modification on RNA, is an emerging and fast-expanding research field.  We identified a protein complex that governs the formation of one type of mRNA methylation in mammalian cells (Nature Cell Biology 16 (2): 191-8, Feb. 2014). Using loss-of-function studies, we reported the requirement of mRNA methylation in embryonic and neural stem cells (Nature Neuroscience 21 (2): 195-206, Feb. 2018). We are now expanding the research towards understanding the role of RNA epigenetics in cancer stem cells.

Successful candidates will be part of a stimulating and collaborative scientific environment with cutting-edge instrumentation and facilities.

TO APPLY: Interested candidates should apply online to the SBP career site by submitting one PDF document with a cover letter, CV, names and contact information of three references.

Primary Responsibilities

• Be the driving force to move projects forward
• Master new knowledge / methods quickly in a fast-growing research field
• Independently design and perform experiments with a high degree of complexity, and troubleshoot with high efficiency
• Produce results with high-quality
• Be able to analyze and interpret data from different sources and draw relevant conclusions
• Demonstrate flexibility in adapting methods and skills according to evolving project priorities
• Write manuscripts and grants
• Present results at internal and external meetings
• Accurately document experiments
• Work collaboratively across lab functions and train other junior lab staff as needed

Required Skills Required Experience

• Ph.D. degree in Science is required
• Strong training in epigenetics and/or stem cell biology is preferred

Knowledge, Skills and/or Abilities

• Highly motivated, committed, and goal-focused
• Strong publication record is a must
• Demonstrated independence, critical thinking, multi-tasking, and problem-solving skills.
• The ability to handle multiple projects and deadlines
• Excellent presentation, verbal, and written communication skills
• Possess strong attention to detail, analytical, time management skills
• Possess outstanding communication and interpersonal skills
• Embody the Institute's core values of Commitment, Collaboration, Communication, Community and Compassion

Sanford Burnham Prebys Medical Discovery Institute is an Equal Opportunity Employer – M/F/Veteran/Disability – committed to the hiring, advancement, and fair treatment of all individuals. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, protected veteran status, or any other protected status as designated by federal, state or local law.  For additional information about your rights as an applicant, click HERE.