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Scientist, LNP Discovery

Mote Therapeutics Inc.

Scientist, LNP Discovery

Lexington, MA
Full Time
Paid
  • Responsibilities

    Job Description

    • Assess novel formulations and materials for circular RNA delivery efficacy in a range of biological contexts, especially in vivo
    • Assist in the buildout of formulation and analytical capabilities with focus on delivery with nanoparticle technology, lyophilization and process development for scale up/production
    • Contribute to patent applications related to the delivery technology
    • Foster collaborative relationships across the team and company and engage in a positive and exciting work environment
    • Hire, train, and manage scientists (as needed) to formulate, characterize, develop, and support assessment of efficacy
    • Plan and coordinate animal studies with in vivo team
    • Author technical documents, including Standard Operating Procedures for formulation processes and analytical methods
  • Qualifications

    Qualifications

    Minimum Qualifications:

    • MS/Ph.D. in chemical engineering, chemistry, pharmaceutical sciences, or related field, preferably with industry experience of 4 - 5 years for MS or 1 - 2 years for PhD qualification.
    • Strong track record of productivity in nanoparticle research with an understanding of key challenges in nanoparticle/formulation scale-up and translation
    • Prior experience in developing lyophilization protocols for nanoparticle formulation, and stability testing is a plus
    • Technical proficiency with LNP formulation of RNA and analytical assays for particle characterization
    • A minimum of 2-3 years of experience working with lipid nanoparticles for RNA delivery in any capacity

    Preferred Qualifications:

    • Demonstrated capability in LNP formulation for nucleic acid delivery is highly desired
    • LNP process development and scale-up experience will be preferred
    • Experience with tissue-specific targeted delivery of LNP-nucleic acid formulation is a plus
    • Demonstrated ability to present complex technical topics to a wide range of audiences with varying technical depth
    • Prior experience in training scientists

    Additional Information

    Join Our Team and Grow with Us:

    At our RNA Venture, we aim to outmatch the typical benefits you might see in an early startup. We offer:

    • Financial security through competitive compensation, incentives, and retirement plan
    • Health care and well-being programs including competitive medical, dental, vision & medical benefits
    • Generous paid time off including vacation, sick time, holidays, and winter shutdown
    • 401(k) retirement savings with a generous company match
    • Commuter benefits
    • Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more
    • We continue to optimize our benefits & wellness programs as we grow our organization to make sure they meet our diverse workforce needs
    • The stability of a startup backed by a company with a record of strong financial performance year over year

    Core values

    • Think bigger : Making informed decisions encompassing long-term implications and overall interests.
    • Start tomorrow today : Embracing innovation, promoting product launches, and encouraging an environment fostering experiential learning.
    • Go bold : Displaying courage, responsibility, and commitment.
    • Continue evolving : Embracing active learning and maintaining an open mind.
    • Keep it simple : Seeking truth from facts and solving problems efficiently.

    About Fapon

    Founded in 2001 and headquartered in Guangdong, China, Fapon Group is mainly engaged in product R&D and services of in vitro diagnostics (IVD), biological therapies, and precision diagnostics and treatments. With our core value of "foresee and prepare for what the future demands", Fapon has historically focused on three major businesses: raw material solutions, IVD ecosystem platform service, and intelligent digital diagnosis and treatment. Fapon’s recent expansion into therapeutics was recently marked by success with the receipt of IND approval from the FDA for a differentiated CD47 antibody drug, the first in an a rapidly expanding therapeutics effort.

    With a global footprint, Fapon has established major production and sales (R&D) bases in Beijing, Shenzhen, Shanghai, the United States, Germany, India and other locations throughout the world, forming a global R&D, production, marketing, and service network with products being widely sold in 61 countries and regions.

    You can learn more about us by visiting https://www.fapon.com/f

    An equal-opportunity employer, we welcomes and encourages diversity in our workforce.

    #LI-NW1