Zag Bio was founded with a vision to develop more precise, potent, and impactful medicines for immune-mediated diseases. Zag Bio is working to discover and develop therapies targeted directly to the thymus, with the goal of generating central immune tolerance.

Our technology platform is inspired by the work of co-founder Diane Mathis of Harvard Medical School, and operates across multiple therapeutic platforms, underpinned by a deep technical interrogation of thymus biology. In addition to Dr. Mathis, Zag Bio was co-founded by Alan Crane (Polaris Partners), Jo Viney (Seismic Therapeutics), and John Kulman (Zag Bio). Zag Bio is a stealth mode biotech company, poised for growth in line with our ambition to transform the treatment of immune-mediated diseases.

We are seeking a lab-based Associate Scientist with in vivo pharmacology experience to support the expansion of the Company’s in vivo capabilities.

Job Responsibilities:

Manage the development of in vivo models of autoimmune disease and immune function; plan and execute routine tissue/organ harvest and cell isolation.

Manage in vivo activities including contributing to IACUC protocols, animal ordering, study design, and colony size management.

Continue to learn new in vivo and in vitro techniques to support program goals.

Execute experiments, present data and recommend next steps.

Document research activities and findings in electronic laboratory notebook and reagent registries in keeping with the highest industry standards.

Required Experience:

Hands-on experience with mouse models, including handling, dosing and tissue harvest.

Willingness to learn essential in vivo techniques including ultrasound guided injections, immune cell isolation, T cell functional assays, and/or flow cytometry.

Excellent analytical, organizational, communication, and time management skills

Candidates with experience in autoimmunity, & IV dosing will be given preferential consideration.

Qualifications:

B.S. or equivalent degree in biology, immunology, or a related discipline

Minimum of 1 year of highly relevant industry research experience.

Occasional weekend hours will be required (up to one weekend per month)

Zag Bio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation, or any characteristic protected under applicable law.